{"id":9263,"date":"2021-10-05T13:53:20","date_gmt":"2021-10-05T18:53:20","guid":{"rendered":"https:\/\/www.vanderbilt.edu\/vise\/?p=9263"},"modified":"2021-10-06T07:19:05","modified_gmt":"2021-10-06T12:19:05","slug":"vise-researcher-awarded-2-6m-grant-to-improve-alzheimers-patient-management","status":"publish","type":"post","link":"https:\/\/www.vanderbilt.edu\/vise\/vise-researcher-awarded-2-6m-grant-to-improve-alzheimers-patient-management\/","title":{"rendered":"VISE researcher awarded $2.6M grant to improve Alzheimer\u2019s patient management"},"content":{"rendered":"<p>An electrical and computer engineering professor has received a $2.6 million NIH grant to improve the reliability of techniques to map of structural changes in the brains of people who have Alzheimer\u2019s Disease.<\/p>\n<p>The goal is to identify opportunities for early intervention by developing more effective interventional strategies.<\/p>\n<p><img loading=\"lazy\" class=\"size-full wp-image-7992 alignleft\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2020\/02\/19170734\/landman200.jpg\" alt=\"\" width=\"200\" height=\"200\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2020\/02\/19170734\/landman200.jpg 200w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2020\/02\/19170734\/landman200-150x150.jpg 150w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2020\/02\/19170734\/landman200-80x80.jpg 80w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2020\/02\/19170734\/landman200-100x100.jpg 100w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2020\/02\/19170734\/landman200-190x190.jpg 190w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/>Bennett Landman, who chairs the Department of Electrical and Computer Engineering, leads the four-year project.<\/p>\n<p>\u201cChanges in brain\u2019s white matter are increasingly being understood as a source of early markers of Alzheimer\u2019s disease, and diffusion weighted MRI offers unparalleled opportunities to probe these brain connections,\u201d said Landman.<\/p>\n<p>Alzheimer\u2019s Disease and dementia is significant public health crisis affecting 5.8 million Americans. Only four medications for Alzheimer\u2019s Disease have FDA approval, but none of those medications produce enduring changes in the progression of the disease that lead to cell death.<\/p>\n<p><img loading=\"lazy\" class=\"size-medium wp-image-9268 alignleft\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2021\/10\/19203423\/Landman-graphic-300x125.jpg\" alt=\"\" width=\"300\" height=\"125\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2021\/10\/19203423\/Landman-graphic-300x125.jpg 300w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2021\/10\/19203423\/Landman-graphic-150x62.jpg 150w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2021\/10\/19203423\/Landman-graphic.jpg 315w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>Early detection and diagnosis are imperative to successful patient management, and biomarkers are needed for revaluating new therapies in clinical trials.<\/p>\n<p>\u201cI am enthusiastic about the opportunities in this project to create new technologies for quantifying diffusion weighted MRI targeted for better understanding of Alzheimer\u2019s disease,\u201d Landman said.<\/p>\n<p>The project is funded by the National Institute of Biomedical Imaging and Bioengineering (R01 EB017230).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An electrical and computer engineering professor has received a $2.6 million NIH grant to improve the reliability of techniques to map of structural changes in the brains of people who have Alzheimer\u2019s Disease. The goal is to identify opportunities for early intervention by developing more effective interventional strategies. Bennett Landman, who chairs the Department of&#8230;<\/p>\n","protected":false},"author":670,"featured_media":7992,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true,"_links_to":"","_links_to_target":""},"categories":[12],"tags":[699,701,700,32,231,188,64,31,30],"acf":[],"jetpack_featured_media_url":"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2020\/02\/19170734\/landman200.jpg","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p98pzF-2pp","_links":{"self":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/9263"}],"collection":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/users\/670"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/comments?post=9263"}],"version-history":[{"count":4,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/9263\/revisions"}],"predecessor-version":[{"id":9269,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/9263\/revisions\/9269"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/media\/7992"}],"wp:attachment":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/media?parent=9263"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/categories?post=9263"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/tags?post=9263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}